The human body is a complex and interconnected mechanism of the work of all its components. Each body is responsible for its own functions. In men and women, due to different reproductive systems, different amounts of hormones are released. Androgens are hormones that every person has. If its balance is disturbed, women may develop unwanted vegetation all over the body, acne, irregularities in the menstrual cycle and infertility. In this article, we will consider the concept of a hormone, its functionality, the causes of various diseases and methods of treatment. Also, the editors of the site "bestx.htgetrid.com/en/" have prepared for you a rating of the best antiandrogenic drugs for 2020.
Content
- 1 What are androgens and what is their function in the body
- 2 Hyperandrogenism and the causes of the onset of the disease
- 3 Types and characteristics of antiandrogenic drugs
- 4 Rating of the best antiandrogenic drugs for 2020
- 5 Side effects from the use of medicines
- 6 Indications and contraindications for taking COCs with antiandrogenic effect
What are androgens and what is their function in the body
Androgens are hormones that are produced by the male and female sex glands and the adrenal cortex. These include: testosterone, androsterone, dihydrotestosterone, androstenediol.
These hormones in the male body are responsible for:
- Low timbre of voice;
- Increased vegetation;
- Increased muscle mass;
- Stronger body endurance.
In women, androgens perform the following functions:
- Hair growth in intimate areas;
- Stabilization of menstruation;
- Regulates the functioning of the sweat and fat glands.
Hormone fluctuations are dangerous for both women and men.
In the case of a decrease in the hormone, the male sex increases the timbre of the voice, the growth of hair on the body decreases, weakness appears in the body, and the sperm become very slow, which leads to difficulties in conceiving a child. In women, a decrease leads to a disruption in the menstrual cycle, as well as to the appearance of obvious problems with conceiving and bearing a baby.
The increase in androgens in the body leads to the appearance of a rougher voice, very active hair growth for men. For women, an increase is dangerous because vegetation appears all over the body and face (hirsutism), an active stage of acne appears and infertility occurs.
Hyperandrogenism and the causes of the onset of the disease
Hyperandrogenism is a disease that is an increase in male hormones, namely testosterone. This condition leads women to miscarriage in 15% of cases. Therefore, in the absence of proper treatment, it will be difficult for a woman to become pregnant and bear a child.
Diseases that can increase the level of androgens in a woman's body:
- Polycystic ovary disease;
- Benign and malignant tumors;
- Hypothyroidism;
- Uncontrolled intake of medicines;
- Genetic diseases.
Disease symptoms:
- Hair growth, mainly on the face, chest, back;
- The appearance of bald patches;
- Skin problems (acne, pimples, changing complexion);
- Obesity;
- The likelihood of diabetes;
- Increased blood pressure;
- Problems with heart;
- Violation of the menstrual cycle;
- Risk of miscarriage;
- Infertility;
- Mental problems;
- Fatigue;
- Weakening of immunity.
At the first signs of this disease, patients are prescribed drugs with an antiandrogenic effect that lower the activity of male hormones, the main of which are combined oral contraceptives.
In addition to hyperandrogenism, antiandrogenic drugs are prescribed in the following cases:
- Polycystic ovary syndrome;
- Increased vegetation;
- Alopecia (baldness);
- Facial skin problems (acne);
- The appearance of dandruff in the form of seborrhea pathology;
- Other endocrine pathologies.
Types and characteristics of antiandrogenic drugs
To avoid mistakes when choosing, it is worth knowing what drugs with antiandrogenic action exist, which is undoubtedly one of the important selection criteria.
Type of medicinal product | Characteristic | Examples of |
---|---|---|
COC - combined oral contraceptives | The COC contains estrogen, which enters the liver, thereby stimulating the production of globulin, which reduces testosterone in the blood. Also, progestogens prevent the male hormone from entering the activity phase. The tool reduces the production of the hormone directly in the ovaries | Yarina, Janine, Logest and others. IMPORTANT! All COCs are prescribed exclusively by a doctor who pre-takes the necessary tests to select the optimal drug |
Steroids | Based on synthetic hormones. Each remedy is prescribed based on symptoms: increased hairiness, acne, seborrhea, menopause, tumors. Each drug has an impressive list of contraindications, therefore, funds are prescribed only by a doctor | Androkur, Diane-35, Klimen and others |
Non-steroidal drugs | Less effective, but at the same time cause minimal harm to the body due to "pure" androgens. Due to their structure, the drugs allow you to adjust to a specific hormone | Flutopharm, Dutasteride, Metformin and others |
Herbal remedies | Licorice, cinnamon, flax seeds, Chinese peony - herbal infusions that reduce the level of androgens in a woman's body | Made by yourself or purchased in special stores |
Rating of the best antiandrogenic drugs for 2020
The rating of quality products will help you find out which drug is better to buy, how much the funds cost and proven effectiveness. In the review, the reader will find drugs from the best manufacturers on the drug market. Unfortunately, almost all contraceptives are not budgetary, as they have a proven effect, therefore, in the treatment of problems with high androgen levels, drugs with a narrow prescription and an inexpensive price can be prescribed.
Janine tb. p / o captivity. 2mg + 30mg # 21
A hormonal drug, one of the best, according to buyers. Release form: tablets, lozenges, capsules. Designed for contraception by estrogen and progestogen. Protection against unwanted pregnancy lies in the interaction of substances that stop the ovulation process and significantly change the viscosity of the mucus in the cervical canal.
This interferes with the passage of sperm. If the tablets are taken correctly, without a pass on a special scale (Pearl index), pregnancy is possible in 1 case. The product contains a substance - dienogest, which has an antiandrogenic effect. Thanks to this tool, the patient's menstrual cycle improves, the amount of discharge and the duration of the menstruation days themselves are reduced.
Also, thanks to clinical studies, it has been proven to reduce the risk of ovarian and endometrial cancer. Before starting the appointment, you must carefully study the instructions for use in order to avoid consequences.
It is applied for 21 days continuously, at the same time. After that, you must stop the reception for seven days and start the course again. You need to know that if you are late in taking the pill, the protection effect remains for 12 hours, but with an increase in the term, contraception is significantly reduced. Excluded use during pregnancy and lactation. Average price: 1,100 rubles for 21 pills.
Advantages:
- Effective remedy;
- Antiandrogenic drug.
Disadvantages:
- Lots of side effects;
- An impressive list of contraindications;
- Expensive in price.
Logest others. No. 63
A contraceptive that contains a hormone. Taking pills is only possible from the age of 18, not suitable for teenagers. Protection from unwanted pregnancy occurs due to the mechanism of action of gestodene and ethinyl estradiol. Inhibits the secretion of gonadotropic hormones of the pituitary gland, stops the process of maturation of follicles and, as a result, stops ovulation.
Due to the active substances, the viscosity of the mucus changes, which stops the penetration of sperm. In addition to protection against pregnancy, women experience the installation of the menstrual cycle, the volume of blood loss and a decrease in duration. The hormonal drug reduces anemia, the frequency of dysmenorrhea and excludes the occurrence of ectopic pregnancy.
With constant use of the drug in women, there is a decrease in the manifestation of fibroadenomas and fibrous cysts in the mammary glands, inflammatory diseases of the pelvic organs and endometrial cancer. Also, due to the androgenic effect, the skin of the face is improved by getting rid of acne.
The drug is used for 21 days without interruption. After that, you need to make a seven-day pause, in which menstruation occurs. Before using it, you must consult a doctor and read the instructions for use. Average price: 2,000 rubles for 31 tablets.
Advantages:
- An effective remedy for unwanted pregnancy;
- Eliminates many women's health problems;
- Antiandrogenic effect;
- Minor side effects.
Disadvantages:
- High price;
- There are many contraindications.
Androkur tab. 10mg No. 15
Medicinal product in tablets, capsules and lozenges. Contains a hormone and is intended for people over 18 years of age. Cyproterone is an active substance that has an antiandrogenic effect and stops the effect of androgens in the female body. When taking the drug in women, there is a decrease in hair growth and a decrease in the likelihood of baldness.
The work of the sebaceous glands is also stabilized and the work of the ovarian functions stops, but only for the time of taking the drug. Indications for use in women: alopecia, increased hairiness on the body and face, seborrhea, acne. It has contraindications, therefore, before you start taking it, you should consult a doctor and study the instructions for use. It can also be used by men in the treatment of prostate cancer and hormone imbalances. Average price: 1,500 rubles.
Advantages:
- An effective drug with an antiandrogenic effect;
- Heals many problems with elevated male hormones;
- Suspends the function of the ovaries, which is an additional way to prevent unwanted pregnancy.
Disadvantages:
- High price;
- There are contraindications and side effects;
- Individual intolerance may be caused.
Yarina tab. p.p. 3mg + 0.03mg No. 21
The contraceptive medicine is available in tablets, capsules and lozenges. Designed for girls over 18 years old, as well as for women in the climacteric stage. Drospirenone and Ethinylestradiol are active ingredients. Suppresses ovulation and increases the viscosity of cervical mucus. Menstruation becomes more regular, less painful, and cycle times are shortened. The active substance has an anti-mineralocorticoid effect, which helps to reduce and stabilize weight, and also relieves obvious symptoms of obesity, such as edema.
In addition, the product has an antiandrogenic effect and allows you to get rid of oily hair, skin, and is also suitable for treating acne. The action of this substance is almost identical to the natural hormone progesterone.
It is used one tablet per day for 21 days, after which it is required to interrupt the intake for seven days.There are contraindications and side effects.
Average price: 1,200 rubles.
Advantages:
- Effective COC;
- Eliminates the action of overestimated androgens;
- Can be used during menopause.
Disadvantages:
- High price;
- There are contraindications.
Klymen tab. p / o No. 21
Hormonal medicine for women over 18 years old. Available in capsules, tablets and lozenges. Cyproterone and Estradiol are active ingredients. Contains estrogen - estradiol valerate, which is converted in the human body into the natural 17 β-estradiol. It also contains a derivative of the main female hormone - progesterone. These substances cause effects: gestagenic, antigonadotropic and antiandrogenic type.
Thanks to the tool, the menstrual cycle is established and ovulation is not suppressed, which leads to the stabilization of hormones in the body. Can be used by women of reproductive age and changeover. Thanks to the drug, in women during menopause, the main symptoms are suppressed: hot flashes, increased secretion of the sebaceous glands, nervous excitability, sleep disturbances, irritability, depression, palpitations, headaches accompanied by dizziness, decreased libido, and so on. Relieves acne, seborrhea, alopecia.
It has contraindications and side effects. Average price: 1200 rubles.
Advantages:
- An effective drug for menopause;
- It is also used to regulate the menstrual cycle;
- Has antiandrogenic effect;
- Reduces depression and other symptoms of menopause.
Disadvantages:
- An expensive tool;
- Discharged only as prescribed by a doctor;
- It has contraindications and side effects.
Side effects from the use of medicines
Any medications that are aimed at reducing androgens have side effects that should be considered before using. These include:
- Nausea, vomiting;
- Diarrhea;
- Increased appetite, which can affect weight;
- Insomnia, fatigue;
- Headache, dizziness;
- Effects, depending on the individual intolerance to certain substances;
- Decreased libido;
- Increased feelings of anxiety;
- Depression.
Indications and contraindications for taking COCs with antiandrogenic effect
With an increased level of androgens, a woman, on the recommendation of a doctor, is prescribed a COC drug with an antiandrogenic effect in the case of:
- Menstrual cycle irregularities;
- Facial skin problems;
- Active hairiness on the face, back, intimate places;
- A noticeable set of muscle mass;
- Infertility.
COC is not only protection against unwanted pregnancy, but also an effective treatment against hormone imbalance in the female body.
Contraindications to the use of COCs:
- Heart disease (in particular, coronary artery disease);
- Smoking;
- Tumors with estrogenic nutrition;
- Severe diabetes mellitus;
- Blood clots;
- Other tumors;
- Liver dysfunction.
Androgens are male hormones, and when their levels are elevated, women may develop masculine traits, such as active hairiness, acne, alopotia, increased sweating, and more. How to choose the right remedy Treatment is prescribed by a doctor after the necessary tests.
In practice, COCs with an antiandrogenic effect are often used. These funds not only protect against unwanted pregnancy, but also restore the balance of hormones, thereby reducing the appearance of symptoms of hyperandrogenism. Thanks to the presented overview of the tools, the reader will select the best option.
You need to know that medications are prescribed by a doctor and before use, you must carefully study the instructions for use. If you have experience using these tools described in the rating or other options, tell us about it in the comments.